Mewgenics

Breed an army of strange cats and send them into turn-based roguelike battles, from the makers of The Binding of Isaac.

Released PC PS5 Xbox Nintendo Strategy Simulation

8 Sept 2026 · $29.99

About Mewgenics

Mewgenics, the long-gestating cat-breeding tactics game from The Binding of Isaac creators Edmund McMillen and Tyler Glaiel, hit consoles in September 2026 after its earlier PC debut. Players draft abilities, collect items and manipulate genetics across generations to build the ultimate feline fighting force. Its mix of deep breeding systems and grotesque humor makes every lineage uniquely unhinged.

• Steam Achievements
• Full controller support
• Steam Cloud
• Family Sharing

Storyline

Mewgenics is set in Boon County, a mostly-dilapidated area in the United States. The game's story is "pretty light", having the player "do the bidding of an incompetent scientist". The player character is a cat lady who is defibrillated at the start of the game, by a cat-obsessed scientist named Dr. Thomas A. Beanies. Beanies gives the player two cats before sending them off to their house, with no instructions beyond acquiring as many cats as possible and performing eugenics on them to make them stronger. As the player advances by exploring and battling further away from their house, various threats emerge to attack their house. Eventually, an earthquake shakes Beanies' lab, causing the animals he was experimenting on to drive him out of it. Beanies blames the player for this, and banishes them. However, he promptly recalls them and has them use a time machine in the lab in an attempt to reverse his misfortune. After travels to the far past and far future fail to produce any change in Beanies' position, he has the player place antennas in the past and future to open a gateway to "the Infinite" to find and kill God. When God immediately starts regenerating after being defeated by the player, Beanies concludes that the only way to kill God is to "nuke the fetal Christ child". After completing several quests to assemble a nuclear bomb, the player returns to the Infinite to re-confront God and use the bomb to destroy God's "Child", which takes the form of a cat fetus. Before the bomb is activated, Dr. Beanies appears via hologram to give a speech about his motives to God; 35 years in the past, his pet cat Stacy died, and despite countless attempts to clone her Beanies was unable to truly recreate her. He believes that this is because God took her soul, and now wants to take revenge on God by taking away his child. If the player refuses to activate the bomb, Beanies attempts to convince them to do so by reminding them of the fate of their son, in the process revealing that the player is Magdalene O. Moriah, the mother of Isaac, the protagonist of McMillen's game The Binding of Isaac; if the player continues to refuse, Beanies activates the bomb himself. As the…

Gameplay

Mewgenics is a tactical role-playing game divided into two stages: combat and cat breeding. At the beginning of the game, the player is assigned a team of four cats, which feature character classes, such as hunter, mage, tank, and fighter. The cats have varying statistics, as well as access to mana reserves, which influence their roles and performance. The cats may be additionally enhanced by equipping clothing and other paraphernalia. The combat portion of the game takes place, principally, on a procedurally-generated grid with a two-dimensional isometric perspective, where the team must eliminate all the enemies before advancing. The combatants may take a move action, use an active ability, and get benefit from passive abilities. The combat is heavily influenced by the environment, including weather and foliage, the latter of which can work for and against the cats. If a cat loses all its hit points, it will be incapacitated yet remain in the battle, though it will suffer long-term consequences in the form of injuries, such as a broken paw, which applies negative stat penalties. An incapacitated cat can still be killed if it takes three additional hits. Should a cat die, its items will be lost, including any exclusive rarities that may only drop once. After a successful battle, a random cat levels up, thereby enhancing its abilities. Breeding, one of the game's essential mechanics, comes into play once the player has completed their initial run. Surviving cats return to the house hub, inheriting their statistics as well as equipment that may be used by other cats. While cats who finish a run are retired and no longer selectable for further runs, two cats in the same room may mate, resulting in the breeding of a new cat that inherits their parents' traits. Inherited traits may produce cats that are ideal for further runs. Inbreeding, the act of breeding cats with closely related parents, can results in offspring with birth defects tied to inbreeding, which have negative effects tied to them. Cats also have a daily chance to develop mutations. Mutations are not inherently harmful; they typically modify a cat’s stats through trade-offs, such as increasing one…